tadalafil (Cialis) atorvastatin; sildenafil; albuterol; gabapentin; estradiol; pantoprazole; amoxicillin; rosuvastatin; ondansetron.Do not chew on it or break it apart. Tadalafil may cause side effects. John’s wort. You will still need to be sexually stimulated to be able to get an erection and maintain it. Swallow the pill whole. Taking more than 1 dose every 24 hours can cause heart issues and other problems.heart attack symptoms – chest pain or pressure, pain spreading to your jaw or shoulder, nausea, sweating. Common tadalafil side effects may include: headache; flushing (warmth, redness, or tingly feeling); nausea, upset stomach; stuffy nose; or. muscle pain, back pain, pain in your arms, legs, or back. This is not a complete list of side. Cialis lasts up to 36 hours in the body, while Viagra lasts 4–6 hours in the body. Both are taken 30 minutes before sex. Cialis can cause limb pain, while Viagra can cause vision change, rash. Tadalafil (Cialis) is taken by mouth either as needed before sexual activity or once daily for erectile dysfunction (ED).It’s also taken once daily to treat symptoms from an enlarged prostate (benign prostatic hyperplasia, or BPH).Tadalafil (Cialis) is available both as brand-name and generic tablets. Common side effects of this medication include .Cialis Daily helps to prevent erectile dysfunction 24 hours a day. Taking Cialis does not mean you are guaranteed to get an erection. Just make sure you take it at the same time every day. It can also interact with many medicines, particularly nitrates used in some types of heart disease and blood pressure medicines. Mechanism of action[ edit ] Penile erection during sexual stimulation is caused by increased penile blood flow resulting from the relaxation of penile arteries and the smooth muscle of the corpus cavernosum.