Dr. Pearlman says it can often take months to get an appointment with a healthcare provider who can prescribe the medications commonly used to treat ED. But, even with the OTC .Key facts It usually takes 30 to 60 minutes for sildenafil to work for erectile dysfunction. When choosing one, tell your doctor or other health care professional what your preferences are, such as cost, ease of use, how long the drug’s effects last and side effects. Pearlman says the availability of an easy-to-access treatment for men dealing with ED is welcome news. Your healthcare provider will discuss which dose is right for you. Medicines that you take by mouth are called oral medicines. Tadalafil Cialis.Roman is a telehealth prescription service and online pharmacy that provides prescription Cialis for ED and a host of other conditions, like hair loss, cold sores, and premature ejaculation. When. This medicine is available on prescription and you can also buy it from most pharmacies. It comes as standard tablets, chewable tablets, and as a liquid that you swallow. Key facts. It usually takes 30 to 60 minutes for sildenafil to work for erectile dysfunction. You can take it up to 4 hours before you want to have sex.  · Descriptions. Sildenafil is used to treat men who have erectile dysfunction (also called sexual impotence). Sildenafil belongs to a group of medicines called phosphodiesterase 5 (PDE5) inhibitors. These medicines prevent an enzyme called phosphodiesterase type-5 from working too quickly. The penis is one of the areas where .How long does it take for Cialis to peak? It might be a while before MED is available at your local pharmacy. A newer form of the medicine that dissolves on the tongue might work faster than the pill that you swallow. That means eating healthy foods, exercising, getting good sleep, limiting stress, and treating other health conditions that might cause ED, like high blood pressure, heart disease, diabetes, obesity, and low testosterone, Dr. Kidney disease that needs to be treated with dialysis. This medicine is available only with your doctor’s prescription. You’ll soon start receiving the latest Mayo Clinic health information you requested in your inbox.