Best Low Cost: GoodRx Fastest Delivery: Blink Health: Sesame Sign Up Now Key Specs Cost: Consultation prices vary based on the prescriber; $5 generic .Cialis was also investigated in combination with finasteride, another BPH medication, in another trial. Sexual activity may be a strain on your heart, especially if you have heart disease. In trials investigating Cialis, the majority of participants receiving the drug experienced a significant improvement in ED and maintained an erection. When choosing one, tell your doctor or other health care professional what your preferences are, such as cost, ease of use, how long the drug’s effects last and side effects. Do not stop taking tadalafil without talking to your doctor.Yes, Cialis is available as a generic medication called tadalafil. Generic medications are just as effective as the brand. Tadalafil 10 mg is available for about $10 for 10 tablets . Cialis doesn’t work right away. For the as-needed dose, plan to take Cialis at least 30 minutes before sexual activity, but bear in mind it may take as long as 2 hours to take effect. How Cialis Works. Tadalafil and other PDE5 inhibitors primarily work by inducing muscle relaxation. Tadalafil stops the breakdown of a chemical responsible for relaxing muscles. In ED and PAH, the drug targets muscle cells in blood vessels. When the blood vessel muscle cells relax, this expands the vessel and increases blood flow; this .Also tell your doctor if you have or have ever had pulmonary veno-occlusive disease PVOD; blockage of veins in the lungs ; any condition that affects the shape of the penis; diabetes; high cholesterol; high or low blood pressure; irregular heartbeat; a heart attack or heart failure; angina chest pain ; a stroke; ulcers in the stomach; a bleeding disorder; blood circulation problems; blood cell problems such as sickle cell anemia a disease of the red blood cells , multiple myeloma cancer of the plasma cells , or leukemia cancer of the white blood cells ; or heart, kidney, or liver disease. Your doctor or other health care professional can recommend one for you based on these factors, other health conditions you have and any other medicines you take. Do not take a double dose or more than one dose per day to make up for a missed one. The generic versions are just as effective and much less expensive. While each PDE5 inhibitor differs slightly, they’re very similar in treating erectile dysfunction. Finding an online ED provider can feel overwhelming.