Brand-name Cialis. $20 for a single 5-mg oral tablet; $80 for a single or mg oral tablet; Daily generic Cialis (tadalafil) $8 for a daily mg or 5-mg tablet; Generic Cialis.You may attempt sexual activity at any time between doses. If you ever need emergency medical treatment for a heart problem, the health care providers who treat you will need to know when you last took tadalafil. Symptoms may include sudden urges to urinate urgency , difficulty in starting urination hesitancy , a weak urine stream, and more frequent urination — especially at night. Also tell your doctor if you have or have ever had pulmonary veno-occlusive disease PVOD; blockage of veins in the lungs ; any condition that affects the shape of the penis; diabetes; high cholesterol; high or low blood pressure; irregular heartbeat; a heart attack or heart failure; angina chest pain ; a stroke; ulcers in the stomach; a bleeding disorder; blood circulation problems; blood cell problems such as sickle cell anemia a disease of the red blood cells , multiple myeloma cancer of the plasma cells , or leukemia cancer of the white blood cells ; or heart, kidney, or liver disease. Your doctor may need to change the doses of your medications or monitor you carefully for side effects. Take tadalafil at around the same time every day.The drug comes in low-dose versions that can be taken daily. This means you can have sex at any time, rather than needing to take a pill from time to time as needed like other ED brands. The starting dose for daily-use Cialis is milligrams (mg). If that doesn’t work, you can increase your daily dose up to 5 mg. Tadalafil (Cialis) is used to treat erectile dysfunction (ED, impotence; inability to get or keep an erection), and the symptoms of benign prostatic hyperplasia (BPH; an enlarged prostate) which include difficulty urinating (hesitation, dribbling, weak stream, and incomplete bladder emptying), painful urination, and urinary frequency and urgency in adult men. Brand-name Cialis. $20 for a single 5-mg oral tablet; $80 for a single or mg oral tablet; Daily generic Cialis (tadalafil) $8 for a daily mg or 5-mg tablet; Generic Cialis.Do not stop taking tadalafil without talking to your doctor. However, because sexual stimulation is required to initiate the local penile release of nitric oxide, tadalafil’s inhibition of PDE5 will have no effect without sexual stimulation. Mechanism of action[ edit ] Penile erection during sexual stimulation is caused by increased penile blood flow resulting from the relaxation of penile arteries and the smooth muscle of the corpus cavernosum. What Are the Symptoms of Erectile Dysfunction? What side effects can this medication cause? Brand names Why is this medication prescribed? Your doctor will probably tell you not to take tadalafil if you are taking street drugs containing nitrates.